Publikationen
Oxidized lipids from sunflower oil modulate fatty acid uptake in Caco-2 cells through regulation of fatty acid transporters. |
Weight loss induced by calorie restriction in mice is associated with a higher sweet taste response and increased fungiform papillae density. |
Role of homovanillic acid esters in the regulation of skin inflammatory pathways and their effect on tight junction protein expression. |
Long-Term Exposure to Sucrose during the Differentiation Process Increases Permeability Independently of TAS1R3 in In Vitro Models of the Intestinal Barrier Function |
Novel Perspective on the Plasticity of Taste Perception: Is Food- and Exercise-Induced Inflammation Associated with Sweet Taste Sensitivity and Preference? |
Dipeptidyl-peptidase 4 (DPP4) mediates fatty acid uptake inhibition by glucose via TAS1R3 and GLUT-2 in Caco-2 enterocytes Heliyon 2024-05 | Journal article DOI: 10.1016/j.heliyon.2024.e30329 Contributors: Verena Preinfalk; Isabella Kimmeswenger; Veronika Somoza; Barbara Lieder |
Development and In Vivo Evaluation of Small-Molecule Ligands for Positron Emission Tomography of Immune Checkpoint Modulation Targeting Programmed Cell Death 1 Ligand 1 Journal of Medicinal Chemistry 2024-03-14 | Journal article DOI: 10.1021/acs.jmedchem.3c02342 Contributors: Karsten Bamminger; Verena Pichler; Chrysoula Vraka; Tanja Limberger; Boryana Moneva; Katharina Pallitsch; Barbara Lieder; Anna Sophia Zacher; Stefanie Ponti; Katarína Benčurová et al. |
On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach Pharmaceuticals 2023-07-24 | Journal article DOI: 10.3390/ph16071051 Contributors: Karsten Bamminger; Verena Pichler; Chrysoula Vraka; Tina Nehring; Katharina Pallitsch; Barbara Lieder; Marcus Hacker; Wolfgang Wadsak |
Human Gingival Fibroblasts as a Novel Cell Model Describing the Association between Bitter Taste Thresholds and Interleukin-6 Release |
Impact of lactisole on the time-intensity profile of selected sweeteners in dependence of the binding site Food chemistry: X 2022 | Journal article DOI: 10.1016/j.fochx.2022.100446 Part of ISSN: 2590-1575 |
Individual Sweet Taste Perception Influences Salivary Characteristics After Orosensory Stimulation With Sucrose and Noncaloric Sweeteners Frontiers in nutrition 2022 | Journal article DOI: 10.3389/fnut.2022.831726 Part of ISSN: 2296-861X |
Long-Term Consumption of a Sugar-Sweetened Soft Drink in Combination with a Western-Type Diet Is Associated with Morphological and Molecular Changes of Taste Markers Independent of Body Weight Development in Mice Nutrients 2022-01-29 | Journal article DOI: 10.3390/nu14030594 Contributors: Barbara Lieder; Jozef Čonka; Agnes T. Reiner; Victoria Zabel; Dominik Ameur; Mark M. Somoza; Katarína Šebeková; Peter Celec; Veronika Somoza |
Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture Journal of Agricultural and Food Chemistry 2021-11-17 | Journal article DOI: 10.1021/acs.jafc.0c07058 Contributors: Johanna Tiroch; Sonja Sterneder; Antonella Di Pizio; Barbara Lieder; Kathrin Hoelz; Ann-Katrin Holik; Marc Pignitter; Maik Behrens; Mark Somoza; Jakob P. Ley et al. |
Gastric Serotonin Biosynthesis and Its Functional Role in L-Arginine-Induced Gastric Proton Secretion International Journal of Molecular Sciences 2021-05-30 | Journal article DOI: 10.3390/ijms22115881 Contributors: Ann-Katrin Holik; Kerstin Schweiger; Verena Stoeger; Barbara Lieder; Angelika Reiner; Muhammet Zopun; Julia K. Hoi; Nicole Kretschy; Mark M. Somoza; Stephan Kriwanek et al. |
Sweetness Perception is not Involved in the Regulation of Blood Glucose after Oral Application of Sucrose and Glucose Solutions in Healthy Male Subjects Molecular Nutrition & Food Research 2021-01 | Journal article DOI: 10.1002/mnfr.202000472 Contributors: Verena Grüneis; Kerstin Schweiger; Claudia Galassi; Corinna M. Karl; Julia Treml; Jakob P. Ley; Jürgen König; Gerhard E. Krammer; Veronika Somoza; Barbara Lieder |
TRPA1 Agonist Cinnamaldehyde Decreases Adipogenesis in 3T3-L1 Cells More Potently than the Non-agonist Structural Analog Cinnamyl Isobutyrate ACS Omega 2020-12-29 | Journal article DOI: 10.1021/acsomega.0c05083 Contributors: Julia K. Hoi; Barbara Lieder; Beatrix Liebisch; Christiane Czech; Joachim Hans; Jakob P. Ley; Veronika Somoza |
Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects Nutrients 2020-10-14 | Journal article DOI: 10.3390/nu12103133 Contributors: Kerstin Schweiger; Verena Grüneis; Julia Treml; Claudia Galassi; Corinna M. Karl; Jakob P. Ley; Gerhard E. Krammer; Barbara Lieder; Veronika Somoza |
Structure-dependent effects of sweet and sweet taste affecting compounds on their sensorial properties Food Chemistry: X 2020-09 | Journal article DOI: 10.1016/j.fochx.2020.100100 Contributors: Corinna M. Karl; Martin Wendelin; Dariah Lutsch; Gerhard Schleining; Klaus Dürrschmid; Jakob P. Ley; Gerhard E. Krammer; Barbara Lieder |
In Vitro Digestion of Grape Seed Oil Inhibits Phospholipid-Regulating Effects of Oxidized Lipids Biomolecules 2020-05-02 | Journal article DOI: 10.3390/biom10050708 Contributors: Sarah Fruehwirth; Sofie Zehentner; Mohammed Salim; Sonja Sterneder; Johanna Tiroch; Barbara Lieder; Martin Zehl; Veronika Somoza; Marc Pignitter |
Correction to Structure-Dependent Effects of Cinnamaldehyde Derivatives on TRPA1-Induced Serotonin Release in Human Intestinal Cell Models Journal of Agricultural and Food Chemistry 2020-04-29 | Journal article DOI: 10.1021/acs.jafc.0c02180 Contributors: Barbara Lieder; Julia Hoi; Nathalie Burian; Joachim Hans; Ann-Katrin Holik; Leopoldo Raul Beltran Marquez; Jakob P. Ley; Hanns Hatt; Veronika Somoza |
Structure-dependent effects of cinnamaldehyde-derivatives on TRPA1 induced serotonin release in human intestinal cell models Journal of Agricultural and Food Chemistry 2020-03-12 | Journal article DOI: 10.1021/acs.jafc.9b08163 Part of ISSN: 0021-8561 Part of ISSN: 1520-5118 |
Identification of Cinnamaldehyde as Most Effective Fatty Acid Uptake Reducing Cinnamon-Derived Compound in Differentiated Caco-2 Cells Compared to Its Structural Analogues Cinnamyl Alcohol, Cinnamic Acid, and Cinnamyl Isobutyrate Journal of Agricultural and Food Chemistry 2019 | Journal article DOI: 10.1021/acs.jafc.9b04274 EID: 2-s2.0-85073763898 Contributors: Hoi, J.K.; Lieder, B.; Pignitter, M.; Hans, J.; Ley, J.P.; Lietard, J.; Hoelz, K.; Somoza, M.; Somoza, V. |
Wheat Protein Hydrolysate Fortified With l‐Arginine Enhances Satiation Induced by the Capsaicinoid Nonivamide in Moderately Overweight Male Subjects Molecular Nutrition & Food Research 2019-12 | Journal article DOI: 10.1002/mnfr.201900133 Contributors: Verena Stoeger; Barbara Lieder; Johanna Riedel; Kerstin Schweiger; Julia Hoi; Veronika Ruzsanyi; Martin Klieber; Petra Rust; Joachim Hans; Jakob P Ley et al. |
Biological Evaluation of Natural and Synthesized Homovanillic Acid Esters as Inhibitors of Intestinal Fatty Acid Uptake in Differentiated Caco-2 Cells Molecules 2019-10-07 | Journal article DOI: 10.3390/molecules24193599 Contributors: Barbara Lieder; Joachim Hans; Fabia Hentschel; Katrin Geissler; Jakob Ley |
Only aG al bound to lipids, but not to proteins, is transported across enterocytes as an IgE reactive molecule that can induce effector cell activation Allergy 2019-05-18 | Journal article DOI: 10.1111/all.13873 Part of ISSN: 0105-4538 Part of ISSN: 1398-9995 |
Cinnamyl Isobutyrate Decreases Plasma Glucose Levels and Total Energy Intake from a Standardized Breakfast: A Randomized, Crossover Intervention Molecular Nutrition and Food Research 2018 | Journal article DOI: 10.1002/mnfr.201701038 EID: 2-s2.0-85052755728 Contributors: Hochkogler, C.M.; Hoi, J.K.; Lieder, B.; Müller, N.; Hans, J.; Widder, S.; Ley, J.P.; Somoza, V. |
Identification of bitter-taste intensity and molecular weight as amino acid determinants for the stimulating mechanisms of gastric acid secretion in human parietal cells in culture. Journal of agricultural and food chemistry 2018-06 | Journal article DOI: 10.1021/acs.jafc.8b01802 PMID: 29879844 Contributors: Stoeger V; Liszt KI; Lieder B; Wendelin M; Zopun M; Hans J; Ley JP; Krammer GE; Somoza V |
Non-caloric sweeteners induce peripheral serotonin secretion via a T1R3-dependent pathway in human gastric cells in culture. Journal of agricultural and food chemistry 2018-06 | Journal article DOI: 10.1021/acs.jafc.8b02071 PMID: 29874909 Contributors: Zopun M; Lieder B; Holik AK; Ley JP; Hans J; Somoza V |
Capsaicin and nonivamide similarly modulate outcome measures of mitochondrial energy metabolism in HepG2 and 3T3-L1 cells. Food & function 2018-02 | Journal article DOI: 10.1039/c7fo01626c PMID: 29362767 Contributors: Hochkogler CM; Lieder B; Schachner D; Heiss E; Schröter A; Hans J; Ley JP; Krammer GE; Somoza V |
The flavanone homoeriodictyol increases SGLT-1-mediated glucose uptake but decreases serotonin release in differentiated Caco-2 cells. 2017 | Journal article DOI: 10.1371/journal.pone.0171580 PMID: 28192456 PMC: PMC5305062 Contributors: Lieder B; Hoi JK; Holik AK; Geissler K; Hans J; Friedl B; Liszt K; Krammer GE; Ley JP; Somoza V |
The Advanced Glycation End Product N(ϵ) -Carboxymethyllysine and its Precursor Glyoxal Increase Serotonin Release from Caco-2 cells. Journal of cellular biochemistry 2017-10 | Journal article DOI: 10.1002/jcb.26439 PMID: 29052845 |
Appetite-Inducing Effects of Homoeriodictyol: Two Randomized, Cross-Over Interventions. Molecular nutrition & food research 2017-08 | Journal article DOI: 10.1002/mnfr.201700459 PMID: 28834253 |
Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. Proceedings of the National Academy of Sciences of the United States of America 2017-07 | Journal article DOI: 10.1073/pnas.1703728114 PMID: 28696284 PMC: PMC5544304 |
A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects. 2017-05 | Journal article DOI: 10.1002/mnfr.201600731 PMID: 28012242 Contributors: Hochkogler CM; Lieder B; Rust P; Berry D; Meier SM; Pignitter M; Riva A; Leitinger A; Bruk A; Wagner S et al. |
The Alkamide trans-Pellitorine Targets PPARγ via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes Frontiers in Pharmacology 2017-05-31 | Journal article DOI: 10.3389/fphar.2017.00316 Part of ISSN: 1663-9812 |
Sensory active piperine analogues from Macropiper excelsum and their effects on intestinal nutrient uptake in Caco-2 cells. 2017-03 | Journal article DOI: 10.1016/j.phytochem.2016.12.016 PMID: 28065397 Contributors: Obst K; Lieder B; Reichelt KV; Backes M; Paetz S; Geißler K; Krammer G; Somoza V; Ley JP; Engel KH |
Nonivamide, a capsaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear cells and U-937 macrophages. 2017-02 | Journal article DOI: 10.1002/mnfr.201600474 PMID: 27666931 Contributors: Walker J; Ley JP; Schwerzler J; Lieder B; Beltran L; Ziemba PM; Hatt H; Hans J; Widder S; Krammer GE et al. |
N(ϵ) -Carboxymethyllysine Increases the Expression of miR-103/143 and Enhances Lipid Accumulation in 3T3-L1 Cells. 2016-10 | Journal article DOI: 10.1002/jcb.25576 PMID: 27137869 PMC: PMC4982050 Contributors: Holik AK; Lieder B; Kretschy N; Somoza MM; Held S; Somoza V |
Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells. 2015-06 | Journal article DOI: 10.1002/jcb.25052 PMID: 25704235 PMC: PMC4949678 Contributors: Rohm B; Holik AK; Kretschy N; Somoza MM; Ley JP; Widder S; Krammer GE; Marko D; Somoza V |
Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake without TRPV1 activation and increase acetyl-coenzyme A synthetase activity in Caco-2 cells. 2015-01 | Journal article DOI: 10.1039/c4fo00435c PMID: 25422952 Contributors: Rohm B; Riedel A; Ley JP; Widder S; Krammer GE; Somoza V |
Structure-dependent effects of pyridine derivatives on mechanisms of intestinal fatty acid uptake: regulation of nicotinic acid receptor and fatty acid transporter expression. 2014-07 | Journal article DOI: 10.1016/j.jnutbio.2014.03.002 PMID: 24767308 Contributors: Riedel A; Lang R; Rohm B; Rubach M; Hofmann T; Somoza V |
The capsaicin analog nonivamide decreases total energy intake from a standardized breakfast and enhances plasma serotonin levels in moderately overweight men after administered in an oral glucose tolerance test: a randomized, crossover trial. 2014-06 | Journal article DOI: 10.1002/mnfr.201300821 PMID: 24753478 Contributors: Hochkogler CM; Rohm B; Hojdar K; Pignitter M; Widder S; Ley JP; Krammer GE; Somoza V |
Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway. 2013-11 | Journal article DOI: 10.1002/mnfr.201200846 PMID: 23929722 Contributors: Rohm B; Holik AK; Somoza MM; Pignitter M; Zaunschirm M; Ley JP; Krammer GE; Somoza V |
Simultaneous light-directed synthesis of mirror-image microarrays in a photochemical reaction cell with flare suppression. 2013-09 | Journal article DOI: 10.1021/ac4024318 PMID: 23968455 PMC: PMC3776564 Contributors: Sack M; Kretschy N; Rohm B; Somoza V; Somoza MM |
N(ε)-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells. 2013-07 | Journal article DOI: 10.1039/c3fo60097a PMID: 23759926 Contributors: Holik AK; Rohm B; Somoza MM; Somoza V |
Biosynthesis of the respiratory toxin bongkrekic acid in the pathogenic bacterium Burkholderia gladioli. 2012-09 | Journal article DOI: 10.1016/j.chembiol.2012.07.022 PMID: 22999884 Contributors: Moebius N; Ross C; Scherlach K; Rohm B; Roth M; Hertweck C |
Caffeine dose-dependently induces thermogenesis but restores ATP in HepG2 cells in culture. 2012-09 | Journal article DOI: 10.1039/c2fo30053b PMID: 22710994 Contributors: Riedel A; Pignitter M; Hochkogler CM; Rohm B; Walker J; Bytof G; Lantz I; Somoza V |
Identification of coffee components that stimulate dopamine release from pheochromocytoma cells (PC-12) Food and Chemical Toxicology 2012-02 | Journal article DOI: 10.1016/j.fct.2011.09.041 Part of ISSN: 0278-6915 |
Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli. 2010-04 | Journal article DOI: 10.1039/b925483h PMID: 20237660 Contributors: Rohm B; Scherlach K; Hertweck C |
Toxin production by bacterial endosymbionts of a Rhizopus microsporus strain used for tempe/sufu processing. 2010-01 | Journal article DOI: 10.1016/j.ijfoodmicro.2009.10.010 PMID: 19942312 Contributors: Rohm B; Scherlach K; Möbius N; Partida-Martinez LP; Hertweck C |