Román-Carrasco P, Klug C, Hemmer W, Focke-Tejkl M, Raith M, Grosinger I et al. Bos d 13, A Novel Heat-Stable Beef Allergen. Molecular Nutrition and Food Research. 2023 Aug;67(16):2200601. doi: 10.1002/mnfr.202200601
Bamminger K, Pichler V, Vraka C, Nehring T, Pallitsch K, Lieder B et al. On the Road towards Small-Molecule Programmed Cell Death 1 Ligand 1 Positron Emission Tomography Tracers: A Ligand-Based Drug Design Approach. Pharmaceuticals. 2023 Jul;16(7):1051. doi: 10.3390/ph16071051
Tiroch J, Dunkel A, Sterneder S, Zehentner S, Behrens M, Di Pizio A et al. Human Gingival Fibroblasts as a Novel Cell Model Describing the Association between Bitter Taste Thresholds and Interleukin-6 Release. Journal of Agricultural and Food Chemistry. 2023 Apr 5;71(13):5314-5325. doi: 10.1021/acs.jafc.2c06979
Deck CM, Behrens M, Wendelin M, Ley JP, Krammer GE, Lieder B. Impact of lactisole on the time-intensity profile of selected sweeteners in dependence of the binding site. Food Chemistry: X. 2022 Okt 30;15:100446. doi: 10.1016/j.fochx.2022.100446
Karl CM, Vidakovic A, Pjevac P, Hausmann B, Schleining G, Ley JP et al. Individual Sweet Taste Perception Influences Salivary Characteristics After Orosensory Stimulation With Sucrose and Noncaloric Sweeteners. Frontiers in Nutrition. 2022 Mai 25;9:831726. doi: 10.3389/fnut.2022.831726
Lieder B, Conka J, Mistlberger-Reiner A, Zabel V, Ameur D, Somoza MM et al. Long-Term Consumption of a Sugar-Sweetened Soft Drink in Combination with a Western-Type Diet Is Associated with Morphological and Molecular Changes of Taste Markers Independent of Body Weight Development in Mice. Nutrients. 2022 Feb;14(3):594. doi: 10.3390/nu14030594
Tiroch J, Sterneder S, Di Pizio A, Lieder B, Hoelz K, Holik AK et al. Bitter Sensing TAS2R50 Mediates the trans-Resveratrol-Induced Anti-inflammatory Effect on Interleukin 6 Release in HGF-1 Cells in Culture. Journal of Agricultural and Food Chemistry. 2021 Nov 17;69(45):13339-13349. doi: 10.1021/acs.jafc.0c07058
Holik A-K, Schweiger K, Stoeger V, Lieder B, Reiner A, Zopun M et al. Gastric Serotonin Biosynthesis and Its Functional Role in L-Arginine-Induced Gastric Proton Secretion. International Journal of Molecular Sciences. 2021 Jun;22(11):5881. doi: 10.3390/ijms22115881
Lieder B. Warum ist süß nicht gleich süß?-Sensorische Profile und strukturelle Merkmale von den Süßgeschmack beeinflussenden Molekülen. Die Ernährung: Österreichische Zeitschrift für Wissenschaft, Technik, Recht und Wirtschaft. 2021 Jun;45:31-33.
Grüneis V, Schweiger K, Galassi C, Karl CM, Treml J, Ley JP et al. Sweetness Perception is not Involved in the Regulation of Blood Glucose after Oral Application of Sucrose and Glucose Solutions in Healthy Male Subjects. Molecular Nutrition and Food Research. 2021 Jan;65(2):2000472. doi: 10.1002/mnfr.202000472
Hoi JK, Lieder B, Liebisch B, Czech C, Hans J, Ley JP et al. TRPA1 Agonist Cinnamaldehyde Decreases Adipogenesis in 3T3-L1 Cells More Potently than the Non-agonist Structural Analog Cinnamyl Isobutyrate. ACS Omega. 2020 Dez 29;5(51):33305-33313. doi: 10.1021/acsomega.0c05083
Schweiger K, Grüneis V, Treml J, Galassi C, Karl CM, Ley JP et al. Sweet Taste Antagonist Lactisole Administered in Combination with Sucrose, But Not Glucose, Increases Energy Intake and Decreases Peripheral Serotonin in Male Subjects. Nutrients. 2020 Okt;12(10):1-12. 3133. doi: 10.3390/nu12103133
Karl CM, Wendelin M, Lutsch D, Schleining G, Duerrschmid K, Ley JP et al. Structure-dependent effects of sweet and sweet taste affecting compounds on their sensorial properties. Food Chemistry: X. 2020 Sep 30;7:100100. doi: 10.1016/j.fochx.2020.100100
Frühwirth SF, Zehentner S, Salim M, Sterneder S, Tiroch J, Lieder B et al. In Vitro Digestion of Grape Seed Oil Inhibits Phospholipid-Regulating Effects of Oxidized Lipids. Biomolecules. 2020 Mai;10(5):708. doi: 10.3390/biom10050708
Lieder B, Hoi J, Burian N, Hans J, Holik A-K, Marquez LRB et al. Structure-Dependent Effects of Cinnamaldehyde Derivatives on TRPA1-Induced Serotonin Release in Human Intestinal Cell Models. Journal of Agricultural and Food Chemistry. 2020 Apr 1;68(13):3924-3932. doi: 10.1021/acs.jafc.9b08163
Karl CM, Wendelin M, Lutsch D, Schleining G, Duerrschmid K, Ley JP et al. Identification of structure-based driving forces of sweetness and associated off-notes. Chemical Senses. 2020 Feb;45(2):143-143.
Stoeger V, Lieder B, Riedel J, Schweiger K, Hoi J, Ruzsanyi V et al. Wheat Protein Hydrolysate Fortified With l-Arginine Enhances Satiation Induced by the Capsaicinoid Nonivamide in Moderately Overweight Male Subjects. Molecular Nutrition & Food Research. 2019 Dez;63(23):1900133. doi: 10.1002/mnfr.201900133
Hoi JK, Lieder B, Pignitter M, Hans J, Ley JP, Lietard J et al. Identification of Cinnamaldehyde as Most Effective Fatty Acid Uptake Reducing Cinnamon-Derived Compound in Differentiated Caco-2 Cells Compared to Its Structural Analogues Cinnamyl Alcohol, Cinnamic Acid, and Cinnamyl Isobutyrate. Journal of Agricultural and Food Chemistry. 2019 Okt 23;67(42):11638-11649. doi: 10.1021/acs.jafc.9b04274
Lieder B, Hans J, Hentschel F, Geissler K, Ley J. Biological Evaluation of Natural and Synthesized Homovanillic Acid Esters as Inhibitors of Intestinal Fatty Acid Uptake in Differentiated Caco-2 Cells. Molecules. 2019 Okt;24(19):3599. doi: 10.3390/molecules24193599
Roman-Carrasco P, Lieder B, Somoza V, Ponce M, Szepfalusi Z, Martin D et al. Only α-Gal bound to lipids, but not to proteins, is transported across enterocytes as an IgE-reactive molecule that can induce effector cell activation. Allergy: European journal of allergy and immunology. 2019 Okt;74(10):1956-1968. doi: 10.1111/all.13873
Lieder B, Burian N, Holik A-K, Hans J, Ley J, Somoza V. Serotonin release by the TRPA1-agonist cinnamaldehyde and structural analogues in differentiated Caco-2 cells. Chemical Senses. 2019 Mär;44(3):E42-E43.
Hochkogler CM, Hoi JK, Lieder B, Mueller N, Hans J, Widder S et al. Cinnamyl Isobutyrate Decreases Plasma Glucose Levels and Total Energy Intake from a Standardized Breakfast: A Randomized, Crossover Intervention. Molecular Nutrition & Food Research. 2018 Sep;62(17):1701038. doi: 10.1002/mnfr.201701038
Hoi J, Lieder B, Hans J, Ley J, Somoza V. Cinnamaldehyde inhibits fatty acid uptake and increases serotonin release in Caco-2 cells via a TRP-A1 dependent pathway. American Chemical Society. Abstracts of Papers (at the National Meeting). 2018 Aug 19;256.
Lieder B, Schweiger K, Somoza V. The TRP channel agonists nonivamide and cinnamaldehyde augment cold-induced mitochondrial biogenesis in white adipocytes. in Siegmund B, Leitner E, Hrsg., Flavour Science : Proceedings of the XV Weurman Flavour Research Symposium: 18.-22. September 2017, Graz University of Technology, Austria. 1 Aufl. Graz: Verlag der Technischen Universität Graz. 2018. S. 273 – 280 doi: 10.3217/978-3-85125-593-5
Zopun M, Lieder B, Holik A-K, Ley JP, Hans J, Somoza V. Noncaloric Sweeteners Induce Peripheral Serotonin Secretion via the T1R3-Dependent Pathway in Human Gastric Parietal Tumor Cells (HGT-1). Journal of Agricultural and Food Chemistry. 2018 Jul 11;66(27):7044-7053. doi: 10.1021/acs.jafc.8b02071
Stoeger V, Liszt KI, Lieder B, Wendelin M, Zopun M, Hans J et al. Identification of Bitter-Taste Intensity and Molecular Weight as Amino Acid Determinants for the Stimulating Mechanisms of Gastric Acid Secretion in Human Parietal Cells in Culture. Journal of Agricultural and Food Chemistry. 2018 Jul 4;66(26):6762-6771. doi: 10.1021/acs.jafc.8b01802
Holik A-K, Lieder B, Kretschy N, Somoza MM, Ley JP, Hans J et al. The advanced glycation end product N-epsilon-carboxymethyllysine and its precursor glyoxal increase serotonin release from Caco-2 cells. Journal of Cellular Biochemistry. 2018 Mär;119(3):2731-2741. doi: 10.1002/jcb.26439
Hochkogler CM, Lieder B, Schachner D, Heiss E, Schröter A, Hans J et al. Capsaicin and nonivamide similarly modulate outcome measures of mitochondrial energy metabolism in HepG2 and 3T3-L1 cells. Food and Function. 2018 Feb 1;9(2):1123-1132. doi: 10.1039/c7fo01626c
Hochkogler CM, Liszt K, Lieder B, Stoeger V, Stübler A, Pignitter M et al. Appetite-Inducing Effects of Homoeriodictyol: Two Randomized, Cross-Over Interventions. Molecular Nutrition & Food Research. 2017 Dez;61(12):1700459. doi: 10.1002/mnfr.201700459
Stoeger V, Liszt K, Lieder B, Zopun M, Wendelin M, Hans J et al. Identification of amino acid structural determinants for activating mechanisms of gastric acid secretion. American Chemical Society. Abstracts of Papers (at the National Meeting). 2017 Aug 20;254.
Lieder B, Hans J, Geissler K, Hentschel F, Ley J. Structural determinants of fatty acid uptake inhibition in differentiated Caco-2 cells. American Chemical Society. Abstracts of Papers (at the National Meeting). 2017 Aug 20;254.
Liszt KI, Ley JP, Lieder B, Behrens M, Stoeger V, Reiner-Concin A et al. Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS). 2017 Jul 25;114(30):E6260-E6269. doi: 10.1073/pnas.1703728114
Lieder B, Zaunschirm M, Holik A-K, Ley JP, Hans J, Krammer GE et al. The Alkamide trans-Pellitorine Targets PPAR gamma via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes. Frontiers in Pharmacology. 2017 Mai 31;8:316. doi: 10.3389/fphar.2017.00316
Hochkogler CM, Lieder B, Rust P, Berry D, Meier SM, Pignitter M et al. A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects. Molecular Nutrition & Food Research. 2017 Mai;61(5):1600731. doi: 10.1002/mnfr.201600731
Obst K, Lieder B, Reichelt KV, Backes M, Paetz S, Geissler K et al. Sensory active piperine analogues from Macropiper excelsum and their effects on intestinal nutrient uptake in Caco-2 cells. Phytochemistry. 2017 Mär;135:181-190. doi: 10.1016/j.phytochem.2016.12.016
Lieder B, Hoi JK, Holik A-K, Geissler K, Hans J, Friedl B et al. The flavanone homoeriodictyol increases SGLT-1-mediated glucose uptake but decreases serotonin release in differentiated Caco-2 cells. PLoS ONE. 2017 Feb 13;12(2):e0171580. doi: 10.1371/journal.pone.0171580
Lieder B, Zaunschirm M, Holik A-K, Hans J, Widder S, Ley JP et al. Involvement of TRPA1 in the inhibition of adipogenesis, but not the maturation of 3T3-L1 adipocytes by pellitorine. Chemical Senses. 2017 Feb;42(2):E41-E42.
Walker J, Ley JP, Schwerzler J, Lieder B, Beltran L, Ziemba PM et al. Nonivamide, a capsaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear cells and U-937 macrophages. Molecular Nutrition & Food Research. 2017 Feb;61(2):1600474. doi: 10.1002/mnfr.201600474
Somoza V, Lieder B. Some like it hot-TRPV1 agonists in health and medicine. Chemical Senses. 2017 Feb;42(2):E9-E10.
Holik A-K, Lieder B, Kretschy N, Somoza MM, Held S, Somoza V. N ϵ -Carboxymethyllysine Increases the Expression of miR-103/143 and Enhances Lipid Accumulation in 3T3-L1 Cells. Journal of Cellular Biochemistry. 2016 Okt;117(10):2413-2422. doi: 10.1002/jcb.25576
Hochkogler CM, Lieder B, Rust P, Widder S, Ley JP, Krammer GE et al. Nonivamide, a TRPV1 Agonist, promotes Body Weight Maintenance in healthy overweight Subjects. Chemical Senses. 2015 Sep;40(7):662-663.
Rohm B, Holik A-K, Kretschy N, Somoza MM, Ley JP, Widder S et al. Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells. Journal of Cellular Biochemistry. 2015 Jun;116(6):1153-1163. doi: 10.1002/jcb.25052
Rohm B, Riedel A, Ley JP, Widder S, Krammer GE, Somoza V. Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake without TRPV1 activation and increase acetyl-coenzyme A synthetase activity in Caco-2 cells. Food & Function: linking the chemistry and physics of food with health and nutrition. 2015;6(1):173-185. doi: 10.1039/c4fo00435c
Riedel A, Lang R, Rohm B, Rubach M, Hofmann T, Somoza V. Structure-dependent effects of pyridine derivatives on mechanisms of intestinal fatty acid uptake: regulation of nicotinic acid receptor and fatty acid transporter expression. The Journal of Nutritional Biochemistry. 2014 Jul;25(7):750-757. doi: 10.1016/j.jnutbio.2014.03.002
Hochkogler CM, Rohm B, Hojdar K, Pignitter M, Widder S, Ley JP et al. The capsaicin analog nonivamide decreases total energy intake from a standardized breakfast and enhances plasma serotonin levels in moderately overweight men after administered in an oral glucose tolerance test: A randomized, crossover trial. Molecular Nutrition & Food Research. 2014 Jun;58(6):1282-1290. doi: 10.1002/mnfr.201300821
Lieder B, Holik A-K, Kretschy N, Somoza MM, Widder S, Ley JP et al. The capsaicin-analog nonivamide prevents lipid accumulation via a TRPV1-dependent pathway and regulates related miRNA expression in 3T3-L1 cells. Chemical Senses. 2014 Jan;39(1):107-107.
Rohm B, Holik A-K, Somoza MM, Pignitter M, Zaunschirm M, Ley JP et al. Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway. Molecular Nutrition & Food Research. 2013 Nov;57(11):2008-2018. doi: 10.1002/mnfr.201200846
Sack M, Kretschy N, Rohm B, Somoza V, Somoza MM. Simultaneous Light-Directed Synthesis of Mirror-Image Microarrays in a Photochemical Reaction Cell with Flare Suppression. Analytical Chemistry. 2013 Sep 17;85(18):8513-8517. doi: 10.1021/ac4024318
Holik A-K, Rohm B, Somoza MM, Somoza V. N-epsilon-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells. Food & Function: linking the chemistry and physics of food with health and nutrition. 2013;4(7):1111-1120. doi: 10.1039/c3fo60097a
Rohm B, Holik A-K, Somoza MM, Pignitter M, Ley JP, Krammer GE et al. Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway. American Chemical Society. Abstracts of Papers (at the National Meeting). 2012 Aug 19;244.
Riedel A, Pignitter M, Hochkogler CM, Rohm B, Walker J, Bytof G et al. Caffeine dose-dependently induces thermogenesis but restores ATP in HepG2 cells in culture. Food & Function: linking the chemistry and physics of food with health and nutrition. 2012;3(9):955-964. doi: 10.1039/c2fo30053b
Walker J, Rohm B, Lang R, Pariza MW, Hofmann T, Somoza V. Identification of coffee components that stimulate dopamine release from pheochromocytoma cells (PC-12). Food and Chemical Toxicology. 2012;50(2):390-398. doi: 10.1016/j.fct.2011.09.041
